Unleash the Potential of Synthetics to Accelerate Regenerative Wound Healing
ElectroFiber 3D™ Supports low pH and accelerates regenerative wound healing:
- Bioengineered, resorbable synthetic polymer technology
- Comprised of PGA and PLCL
- Synthetic polymers demonstrates a reduction in pH from 7.4 to 5.9 within 78 hours; to 4 within 2 weeks 9
- Agonistic to microbes 3-8
- Accelerates the wound healing process 1,2,10
- <8 weeks to wound closure 2,10
- Demonstrates a reduction wound associated pain scores after 1st application 1,10
- 2 or fewer applications, on average to closure 2,10
- 510K cleared for the management of partial to full thickness acute and chronic wounds, and burns
Mean PAR for ALL wounds, VLUs, DFUs, and PIs up to 12 weeks2
Chronic Surgical Wound
65 days2
Chronic DFU
42 days2
Chronic PI
77 days2
VLU
30 days2
WHAT IS ELECTROFIBER 3D™ WOUND MATRIX?
IS ELECTROFIBER 3D™ WOUND MATRIX CLEARED AS A 510K MEDICAL DEVICE?
HOW DOES ELECTROFIBER 3D™ WOUND MATRIX DIFFER FROM CTPS?
WHAT IMPACT DOES ELECTROFIBER 3D™ WOUND MATRIX HAVE ON PH?
HOW IS ELECTROFIBER 3D™ WOUND MATRIX APPLIED?
WHAT IS THE TOTAL TIME FOR DEGRADATION OF ELECTROFIBER 3D™ WOUND MATRIX?
Ordering Information
Part #
EF3D-1020
EF3D-1010
EF3D-0505
Size
10x20cm
10x10cm
5x5cm
CM2
200100
25
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2. Kaufman T, Eichenlaub EH, Angel MF, Levin M, Futrell JW (1985) Topical acidification promotes healing of experimental deep partial thickness skin burns: a randomised double-blind preliminary study. Burns 12: 84–90.;
3. Leveen H, Falk G, Borek B, Diaz C, Lynfield Y, Wynkoop B, Mabunda GA et al (1973) Chemical acidification of wounds. An adjuvant to healing and the unfavourable action of alkalinity and ammonia. Ann Surgery 178(6): 745–50.;
4. Jones, E.M., C.A. Cochrane, and S.L. Percival, The Effect of pH on the Extracellular Matrix and Biofilms. Adv Wound Care (New Rochelle), 2015. 4(7): p. 431-439.;
5. Schneider, L.A., et al., Influence of pH on wound-healing: a new perspective for wound-therapy? Arch Dermatol Res, 2007. 298(9): p. 413-20.;
6. Gethin, G., The significance of surface pH in chronic wounds. Wounds UK, 2007 .;
7. B, G., et al., Proteases and pH in chronic wounds. Journal of Wound Care, 2005. 14(2): p. 59-61.;
8. Das A, Sinha M, Datta S, Abas M, Chaffee S, Sen CK, Roy S. Monocyte and macrophage plasticity in tissue repair and regeneration. Am J Pathol. 2015 Oct;185(10):2596-606. doi: 10.1016/j.ajpath.2015.06.001. Epub 2015 Jun 26. PMID: 26118749; PMCID: PMC4607753.;
9. Haller HL, Sander F, Popp D, Rapp M, Hartmann B, Demircan M, Nischwitz SP, Kamolz LP. Oxygen, pH, Lactate, and Metabolism-How Old Knowledge and New Insights Might Be Combined for New Wound Treatment. Medicina (Kaunas). 2021 Nov 1;57(11):1190. doi: 10.3390/medicina57111190. PMID: 34833408; PMCID: PMC8617754.;
10. Kroner, E.; Kaiser, J.S.; Fischer, S.C.; Arzt, E. Bioinspired polymeric surface patterns for medical applications. J. Appl. Biomater. Funct. Mater. 2012, 10, 287–292.;
11. Zieker D, Schäfer R, Glatzle J, Nieselt K, Coerper S, Kluba T, Northoff H, Königsrainer A, Hunt TK, Beckert S. Lactate modulates gene expression in human mesenchymal stem cells. Langenbecks Arch Surg. 2008 May;393(3):297-301. doi: 10.1007/s00423-008-0286-6. Epub 2008 Feb 14. Erratum in: Langenbecks Arch Surg. 2009 Mar;394(2):405. Kluba, Torsten [added]. PMID: 18273635.;
12. Schneider CC, Ateschrang A, Königsrainer I, Glatzle J, Bühler S, Schaefer R, Northoff H, Königsrainer A, Zieker D. Lactate influences the gene expression profile of human mesenchymal stem cells (hMSC) in a dose dependant manner. Cell Physiol Biochem. 2012;30(6):1547-56. doi: 10.1159/000343342. Epub 2012 Dec 10. PMID: 23234875.;
13. Lim, H. W., S.A.B Collins, J.S. Resneck, Jr, et al. 2017. The burden of skin disease in the United States. J. Am. Acad. Dermatol. 76: 958-972.e2.;
14. Driver, V.R., R.J. Snyder, T. Conner-Kerr & T. Thomas. 2014. AAWC Fact Sheet 1: CHRONIC WOUNDS The most important health problem you’ve never heard about. AAWC. Accessed January 24, 2018.;
15. Caroline E. Fife, Kristen A. Eckert, and Marissa J. Carter. Publicly Reported Wound Healing Rates: The Fantasy and the Reality. Advances in Wound Care. Mar 2018.77- 94.http://doi.org/10.1089/wound.2017.0743;
16. Lambert, C. Jake, Aviles, F., et al., The efficacy of a novel 3-D electrospun synthetic polymer matrix (3DESPM) for the management of difficult-to-heal wounds, Symposium on Advanced Wound Care poster presentation, 5.2022;
17. Horn CP, Fierro AL, Lantis JC 2nd. The Shift to Synthetics: A Review of Novel Synthetic Matrices for Wound Closure. Surg Technol Int. 2023 Sep 15;42:75-86. PMID: 37802070.